Institute for Plant Sciences of Montpellier (IPSiM)

• For more than 15 years, our group has been at the forefront of the functional characterization of membrane nitrate transporters (e.g., NRT2.1), and of the identification of their regulatory mechanisms (regulation by nitrate, by whole plant N status, and by photosynthesis).
  See: Lejay et al. 1999, Cerezo et al. 2001, Lejay et al. 2003, Wirth et al. 2007, Lejay et al. 2008, Widiez et al. 2011, Laugier et al. 2012, de Jong et al. 2014, Alvarez et al. 2014.
• We have unravelled a novel mechanism of nitrate sensing involving the dual transport/sensing function of the nitrate transporter (transceptor) NRT1.1/NPF6.3. NRT1.1/NPF6.3 triggers many different responses of the plant to nitrate, including regulation of other nitrate transporters and regulation of lateral root growth.
  See: Muños et al. 2004, Remans et al. 2006, Krouk et al. 2010, Gojon et al. 2011, Bouguyon et al. 2015, Bouguyon et al. 2016.

  See also : prize of the French Academy of sciences: Nitrogen nutrition in plants: root growth guided by protein, and press releases: Les stratégies des plantes pour optimiser l’utilisation des nitrates (in French), Détection des ions minéraux par les plantes : du nouveau pour le nitrate et le phosphate (in French).

• Our group has organized the EMBO Conference Nitrogen2016 (Third International Symposium on the Nitrogen Nutrition of Plants, August 2016, Montpellier, France), and has edited a special issue of the Journal of Experimental Botany associated with this conference (Special Issue: Nitrogen Nutrition in Plants: Rapid Progress and New Challenges).

Bach L✉, Gojon A (2023) Root system growth and development responses to elevated CO2: underlying signalling mechanisms and role in improving plant CO2 capture and soil C storage. Biochem. J., 480(11):753-771

Cassan O, Pimparé L-L, Dubos C, Gojon A, Bach L, Lèbre S, Martin A✉ (2023) A gene regulatory network in Arabidopsis roots reveals features and regulators of the plant response to elevated CO2. New Phytol., (accepted)

Chaput V, Li J, Séré D, Tillard P, Fizames C, Moyano TC, Zuo K, Martin A, Gutiérrez RA, Gojon A, Lejay L✉ (2023) Characterisation of the signalling pathways involved in the repression of root nitrate uptake by nitrate in Arabidopsis thaliana. J. Exp. Bot., (accepted)

Hirt H✉, Al-Babili S, Almeida-Trapp M, Martin A, Aranda M, Bartels D, Bennett MJ, Blilou I, Boer D, Boulouis A, Bowler C, Brunel-Muguet S, Chardon F, Colcombet J, Colot V, Daszkowska-Golec A, Dinneny JR, Field B, Froehlich K, Gardener CH, Gojon A, Gomès E, Gómez Álvarez EM, Gutierrez C, Havaux M, Hayes S, Heard E, Hodges M, Alghamdi AK, Laplaze L, Lauersen KJ, Leonhardt N, Johnson X, Jones JDG, Kollist H, Kopriva S, Krapp A, Lopez-Portillo Masson M, McCabe MF, Merendino L, Molina A, Moreno Ramirez JL, Müller-Röber B, Nicolas M, Nir I, Olivas Orduna I, Pardo-Tomás J, Reichheld J-P, Rodriguez Egea PL, Rouached H, Saad MM, Schlögelhofer P, Singh KA, De Smet I, Stanschewski C, Stra A, Tester M, Walshe C, Weber APM, Weigel D, Wigge PA, Wrzaczek M, Wulff B, Young IM (2023) PlantACT! – how to tackle the climate crisis. Trends Plant Sci., 28(5):537-543

Bäurle I✉, Laplaze L✉, Martin A✉ (2023) Preparing for an uncertain future: molecular responses of plants facing climate change. J. Exp. Bot., 74(5):1297-1302

Gojon A, Cassan O, Bach L, Lejay L, Martin A✉ (2023) The decline of plant mineral nutrition under rising CO2: physiological and molecular aspects of a bad deal. Trends Plant Sci., 28(2):185-198

Séré D, Cassan O, Bellegarde F, Fizames C, Boucherez J, Schivre G, Azevedo J, Lagrange T, Gojon A, Martin A✉ (2022) Loss of Polycomb proteins CLF and LHP1 leads to excessive RNA degradation in Arabidopsis. J. Exp. Bot., 73(16):5400-5413

Charoensawan V✉, Cortijo S✉, Domijan M✉, Negrão S✉ (2022) Multi-disciplinary approaches to plant responses to climate change. Front. Plant Sci., 13:876432

Ruffel S*, Chaput V*, Przybyla-Toscano J, Fayos I, Ibarra C, Moyano TC, Fizames C, Tillard P, O’Brien JA, Gutiérrez RA, Gojon A, Lejay L✉ (2021) Genome-wide analysis in response to nitrogen and carbon identifies regulators for root AtNRT2 transporters. Plant Physiol., 186(1):696-714

Cassan O✉, Lèbre S, Martin A (2021) Inferring and analyzing gene regulatory networks from multi-factorial expression data: a complete and interactive suite. BMC Genomics, 22:387

Chu L-C, Offenborn JN, Steinhorst L, Wu XN, Xi L, Li Z, Jacquot A, Lejay L, Kudla J, Schulze W✉ (2021) Plasma membrane calcineurin B-like calcium-ion sensor proteins function in regulating primary root growth and nitrate uptake by affecting global phosphorylation patterns and microdomain protein distribution. New Phytol., 229(4):2223-2237

Cortijo S, Bhattarai M, Locke JCW✉, Ahnert SE✉ (2020) Co-expression networks from gene expression variability between genetically identical seedlings can reveal novel regulatory relationships. Front. Plant Sci., 11:599464

Jacquot A, Chaput V, Mauriès A, Li Z, Tillard P, Fizames C, Bonillo P, Bellegarde F, Laugier E, Santoni V, Hem S, Martin A, Gojon A, Schulze W, Lejay L✉ (2020) NRT2.1 C-terminus phosphorylation prevents root high affinity nitrate uptake activity in Arabidopsis thaliana. New Phytol., 228(3):1038-1054

Maghiaoui A, Gojon A, Bach L✉ (2020) NRT1.1-centered nitrate signaling in plants. J. Exp. Bot., 71(20):6226-6237

Vidal EA, Alvarez JM, Araus V, Riveras E, Brooks MD, Krouk G, Ruffel S, Lejay L, Crawford NM, Coruzzi GM, Gutiérrez RA✉ (2020) Nitrate 2020: Thirty years from transport to signaling networks. Plant Cell, 32(7):2094-2119

Maghiaoui A*, Bouguyon E*, Cuesta C, Perrine-Walker F, Alcon C, Krouk G, Benková E, Nacry P, Gojon A, Bach L✉ (2020) The Arabidopsis NRT1.1 transceptor coordinately controls auxin biosynthesis and transport to regulate root branching in response to nitrate. J. Exp. Bot., 71(15):4480-4494

Chaput V, Martin A, Lejay L✉ (2020) Redox metabolism: the hidden player in carbon and nitrogen signaling? J. Exp. Bot., 71(13):3816-3826

Bellegarde F, Maghiaoui A, Boucherez J, Krouk G, Lejay L, Bach L, Gojon A, Martin A✉ (2019) The chromatin factor HNI9 and ELONGATED HYPOCOTYL 5 maintain ROS homeostasis under high nitrogen provision. Plant Physiol., 180(1):582-592

Bellegarde F, Herbert L, Séré D, Caillieux E, Boucherez J, Fizames C, Roudier F, Gojon A, Martin A✉ (2018) Polycomb Repressive Complex 2 attenuates the very high expression of the Arabidopsis gene NRT2.1. Sci. Rep.-UK, 8:7905

Bellegarde F, Gojon A, Martin A✉ (2017) Signals and players in the transcriptional regulation of root responses by local and systemic N signaling in Arabidopsis thaliana. J. Exp. Bot., 68(10):2553-2565

Jacquot A, Li Z, Gojon A, Schulze W, Lejay L✉ (2017) Post-translational regulation of nitrogen transporters in plants and microorganisms. J. Exp. Bot., 68(10):2567-2580

• Nationales
  • Nourollah Ahmadi / Emmanuel Guiderdoni, UMR AGAP, Cirad, Montpellier
  • Anne Krapp / Christian Meyer, IJPB, INRA, Versailles
  • François Roudier, UMR RDP, ENS, Lyon
  • Christophe Salon, UMR Agro-écologie, INRA, Dijon
• Internationales
  • Rodrigo Gutiérrez, Université catholique du Chili
  • Waltraud Schulze, Université Hohenheim, Allemagne
  • Dennis Shasha, New York University, Etats Unis
  • Yi-Fang Tsay, Academia Sinica, Taiwan
  • Eva Zazimalova, Czech Academy of Sciences, République Tchèque

• Projet ANR Franco-Taiwanais NITRASENSE (2017-2020)
• Projet Agropolis Fondation GENERICE (2017-2019)
• Projet INRA BAP CLIMNUTR (2017-2018)
• Projet ANR IMANA (2014-2018)
• Projet ANR blanc Franco-Allemand SIPHON (2014-2017)
• Projet INRA BAP ACCESS (2014-2015)
• Projet ANR blanc Franco-Chilien ModelN (2010-2013)
• Projet Agropolis Fondation RHIZOPOLIS (2010-2013)