However, it is often their combination that is of interest. In an article published in the journal Genome Biology, scientists describe a method combining mathematics, genetics and high-performance computing to create exhaustive interaction maps bringing together several tens of billions of interactions between genetic variants and enabling these combinations to be studied. [ CNRS press release ].
Contact : Gabriel Kouk, SYSTEMS team
Carré C*✉, Carluer J-B*, Chaux C, Estoup-Streiff C, Roche N, Hosy E, Mas A✉, Krouk G✉ (2024) Next-Gen GWAS: full 2D epistatic interaction maps retrieve part of missing heritability and improve phenotypic prediction. Genome Biol.
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