Charlotte Lecuyer

Team : Sirene – IPSiM

Supervisor :

Title : The role of chromatin in the regulation of transcriptional variability in plants

Abstract :

Transcriptional variability has been shown to be one of the mechanisms that could enable individuals in a population to survive sudden stress. It is observed in the absence of any genetic or environmental change. Although quite well documented in animals and micro-organisms, knowledge on this subject in plants is not very extensive and the mechanisms behind transcriptional variability are not very well identified. Chromatin could be one of the factors enabling organisms to establish this form of regulation. For this study, a combination of genomic, genetic and imaging approaches will be used to understand the role of chromatin in this regulation, in particular through the use of chromatin mutants.

Teiki Raihauti

Team : MAGE – LEPSE, Phenomen – AGAP

Supervisor : Pierre MARTRE, Christophe PRADAL, Myriam ADAM, Cyrille MIDINGOYI

Title : Semantic and modular representation of crop models

Abstract : The emergence of modeling platforms is driving the inclusion of new processes within models, and increasing interest in their reuse. However, this step requires detailed knowledge of modeling components and solutions, particularly in terms of source code structure. The aim of my thesis is to facilitate the exchange and reuse of these components through a semantic representation shared by culture models. To this end, I am seeking to compile a list of semantic components present in the various platforms, and also to study the connections between these components.

Will Davis

Team : Visiting from SLCU (Cambridge, UK), Sirene – IPSiM

Supervisor : James Locke

Title : ELF3 regulates inter-individual gene expression variability in Arabidopsis

Abstract : Widespread gene expression variability between isogenic plants has previously been characterised in Arabidopsis thaliana and is known to be temporally structured, suggesting a regulatory influence from the circadian clock. In my project, I have examined the role of a key circadian regulator EARLY FLOWERING 3 (ELF3) in buffering variability. Through a range of experimental approaches, I show that ELF3 reduces noise in expression of circadian genes under light dark cycles and affects widespread transcriptional variability on a network specific basis. »