Séminaire IBIP
Les séminaires ont lieu sur le Campus Montpellier SupAgro/INRA de La Gaillarde (2, place P. Viala Montpellier)

Mardi 5 octobre 2010
Amphi 208 (Coeur d’Ecole) à 14h

Adaptation to the host plant drives dual genome evolution in the Irish potato famine pathogen lineage

Sylvain Raffaele
Sainsbury laboratory, UK

Plant pathogens in the lineage of the Irish potato famine organism Phytophthora infestansevolve by host jumps and specialization. The extent to which host jumps and specializationimpact genome evolution remains largely unknown. To determine the selective forcesshaping sequence variation in this lineage, we resequenced six genomes of four sisterspecies. This work revealed uneven evolutionary rates with genes in repeat-rich regionsshowing higher rates of copy number variation, presence/absence polymorphisms, anddN/dS>1. These loci are enriched in genes induced in planta implicating host adaptation ingenome evolution. Genes involved in epigenetic processes are other rapidly evolvingresidents of the gene-sparse regions. These results demonstrate that dynamic genomecompartments enriched in non-coding sequences underpin rapid gene evolution followinghost jumps in this pathogen lineage.


Contact : Tou Cheu Xiong

Contacts IBIP :
Sabine Zimmermann
Marc Lepetit
Christine Granier
Corinne Dasen
Chantal Baracco