Les séminaires ont lieu sur le Campus Montpellier SupAgro/INRA de La Gaillarde (2, place P. Viala Montpellier)
Jeudi 1er octobre 2015
Amphi 206 (Cœur d’Ecole) à 15h
New avenues of research in ABA signaling: membrane targeting and ubiquitylation of ABA receptors
Pedro L. Rodriguez Egea
Instituto de Biologia Molecular y Celular de Plantas / CSIC, Univ. Politécnica, Valencia, Spain
Auxiliary proteins that regulate half-life, trafficking or membrane targeting of ABA receptors represent candidate genes to modulate ABA signalling. ABA receptors are subjected to ubiquitylation at the plasma membrane through the single subunit RING-type E3 ubiquitin ligase RSL1 (Bueso et al., 2014). We have discovered that targeting of ABA receptors by different RSL1/RFA E3s occurs at different cell compartments, which illustrates a novel mechanism to promote the turnover of ABA receptors in plasma membrane, cytosol and nucleus. We have also discovered that calcium-dependent interaction of ABA receptors with membranes is mediated through a new gene family of C2-domain ABA-related (CAR) proteins (Rodriguez et al., 2014).
Contact: Christophe Maurel