Séminaire IBIP
Les séminaires ont lieu sur le Campus Montpellier SupAgro/INRA de La Gaillarde (2, place P. Viala Montpellier)

Jeudi 22 juin 2017
Amphi 206 (Cœur d’Ecole) à 14h

Cell size determination and differential growth regulation

Jürgen Kleine-Vehn
Department of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences, Vienna (BOKU), 1190 Vienna, Austria

Multicellular plants require particularly defined cellular strategies for tissue patterning and expansion, because the encapsulating cell wall literally binds neighbouring cells to each other. This interdependency limits cellular migration and, therefore, imposes outstanding importance to cell size determination and supracellular growth regulation. Phytohormones are central to these regulations and the unravelling of their subcellular working mechanisms bares high biotechnological potential.
My lab is combining cell biological, physiological and developmental genetics
approaches to decipher growth regulation on a sub-cellular, tissue and organ level (e.g. Barbez et al., Nature 2012; Ruiz Rosquete et al., CurrBiol 2013; Löfke et al., eLife 2015; Scheuring et al., PNAS 2016). On a subcellular level, we are particularly interested in cellular organelles, such as the endoplasmic reticulum or the vacuole, and their mechanistic contribution to growth regulation. To address cell size determination and tissue growth in plants, we are utilizing epidermal cell files, displaying shorter (tricho-) and longer (atrichoblast) cell files. This cell biological model system allows us to identify cellular effectors controlling cell sized determination and cellular expansion. The phytohormone auxin provides integrative cues to plant cells and is central to plant growth control. In our ERC funded work, we are currently dissecting the function of PILS putative auxin carriers at the ER and thereby revealing the previously non-anticipated developmental importance of ER-based auxin biology. Our work provides a cell biological view on plant growth regulation.

Contact : Benjamin Péret

Contacts IBIP :
Sabine Zimmermann
Alexandre Martinière
Christine Granier
Chantal Baracco