IBIP seminar

Thursday, October 1, 2015

New avenues of research in ABA signaling: membrane targeting and ubiquitylation of ABA receptors

Pedro L. Rodriguez Egea
Instituto de Biologia Molecular y Celular de Plantas / CSIC, Univ. Politécnica, Valencia, Spain

Auxiliary proteins that regulate half-life, trafficking or membrane targeting of ABA receptors represent candidate genes to modulate ABA signalling. ABA receptors are subjected to ubiquitylation at the plasma membrane through the single subunit RING-type E3 ubiquitin ligase RSL1 (Bueso et al., 2014). We have discovered that targeting of ABA receptors by different RSL1/RFA E3s occurs at different cell compartments, which illustrates a novel mechanism to promote the turnover of ABA receptors in plasma membrane, cytosol and nucleus. We have also discovered that calcium-dependent interaction of ABA receptors with membranes is mediated through a new gene family of C2-domain ABA-related (CAR) proteins (Rodriguez et al., 2014).

Contact: Christophe Maurel

Contacts IBIP :
Sabine Zimmermann
Alexandre Martiniere
Christine Granier
Chantal Baracco