Thursday, March 14, 2019
at 2:00 pm – Amphi 2 (bât. 2bis)
Molecular logic in large-scale receptor interaction networks
Gregor Mendel Institute of Molecular Plant Biology, Vienna, Austria
In plants genomes, an expanded family of cell-surface receptor kinases (RKs) transduce either ‘self’ or ‘non‐self’ signals into changes in nuclear gene expression.
Plant RKs are typically characterized by an extracellular domain, and in most cases, a functional intracellular kinase domain.
Extracellular domains (ECDs) can modulate the activity of signaling competent RKs complexes by controlling ligand specificity and by recruiting appropriate signaling partners.
There is very limited knowledge on the global interaction network ECDs can establish in their resting or ligand-activated functioning modes.
I will present collaborative efforts aimed at discovering novel ligands and ECD interactions in the RKs repertoire of Arabidopsis.
Contact : Hatem Rouached