DIYABC

Do it yourself ABC

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Welcome to the webpage of the software DIYABC :

a user-friendly approach to Approximate Bayesian Computation for inference on population history using molecular markers

by Jean-Marie Cornuet, Filipe Santos and Arnaud Estoup

Centre de Biologie et de Gestion des Populations, INRA, Campus International de Baillarguet, CS30016 34988 Montferrier-sur-Lez, France

Dear DIYABC users,

We would like to inform you that:

We do not have presently the capacity to ensure any technical support (i.e. bug corrections or developments) of the presently available version of DIYABC-v1.0.4.46beta. This is because all our research and developmental resources are presently used for the coding and finalization of a new multiplatform version of DIYABC (v2). We apologize for this inconvenience. You nevertheless can still use the forum to exchange ideas and advises. We hope to have the new multiplatform DIYABC package ready for diffusion to the scientific community around DECEMBER 2012. This new version will include many new useful options including linear discriminant analysis to compute probability of scenarios and SNP datasets analysis. We also hope that it will be more stable than the previous Microsoft Window version of DIYABC.
We found that the cluster version of DIYABC-v1.0.4.46beta to be unstable.
We found that the Microsoft Windows version of DIYABC-v1.0.4.46beta with graphical interface to be unstable in a Microsoft Windows 7 environment (cf. occurrence of unexplained bugs in this environment). DIYABC-v1.0.4.46beta should be hence preferentially used in a Microsoft Windows XP environment.

All the best

The DIYABC developmental team

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It is currently Sun May 26, 2013 12:57 am

DOWNLOADS :

Download the beta release : DIYABC-v1.0.4.46beta.exe

Download the beta documentation : DIYABC v1.0.4.46beta Documentation

**The beta version (V1.*) includes the following new features :

data files can include microsatellite and/or DNA sequence data,

five categories of loci are recognized : autosomal haploid, autosomal diploid, X-linked, Y-linked and mitochondrial. Note that X-linked loci can be used for haplo-diploid species (when both sexes have been sampled).

two options have been added : one for pre-evaluating model-prior combinations and the other one for checking model and posterior distributions,

multithread technology has been implemented to accelerate time-consuming computations when performed on multicore computers.

IMPORTANT NOTE :** The reference table file format has been modified so that this version is incompatible with reference tables obtained with the old v.0.xx versions.

The software DIYABC, as well as the companion notice and manuscript published in Bioinformatics are freely available on this site.

Registering (below) is optional and free. It gives you access to :

DIYABC forum where you can post questions to authors or other users, signal bugs, ...
the linux cluster version
the program sources
older (linux/windows) versions

Summary :

DIYABC is a computer program with a graphical user interface and a fully click-able environment. It allows population biologists to make inference based on Approximate Bayesian Computation (ABC), in which scenarios can be customized by the user to fit many complex situations involving any number of populations and samples. Such scenarios involve any combination of population divergences, admixtures and population size changes. DIYABC can be used to compare competing scenarios, estimate parameters for one or more scenarios, and compute bias and precision measures for a given scenario and known values of parameters (the current version applies to unlinked microsatellite data).

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